Correlations between holo-transcobalamin II, holo-haptocorrin, and total B12 in serum samples from healthy subjects and patients.

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Holo-Transcobalamin Concentrations and Transcobalamin Saturation Reflect Recent Vitamin B12 Absorption Better than Does Serum Vitamin B12

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Holo-transcobalamin concentration and transcobalamin saturation reflect recent vitamin B12 absorption better than does serum vitamin B12.

BACKGROUND We evaluated whether measurement of vitamin B(12)-saturated transcobalamin (holo-TC) concentrations or TC saturation (holo-TC:total TC) reflects active vitamin B(12) absorption in healthy individuals and patients after vitamin B(12) intake. METHODS We obtained blood samples from 31 healthy individuals (age range, 25-57 years) before (days -1 and 0) and after (days 1, 2, and 6) oral...

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Quantification of holo-transcobalamin, a marker of vitamin B12 deficiency.

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1993

ISSN: 0021-9746

DOI: 10.1136/jcp.46.6.537